On July 1, 1998, Pine Rest and Mercy Health (formerly Saint Mary's Health Care), a member of the Trinity Health Services Corporation, and Metro Health formed a Joint Operating Agreement to provide inpatient and partial hospitalization services to benefit the community over the long run.
This venture combines into one jointly operated structure the behavioral health care inpatient and partial hospitalization services previously operated separately by the institutions. Pine Rest is the majority owner and representatives from Pine Rest, Mercy Health, and Metro Health govern the Joint Operating Agreement.

This Joint Operating Agreement has been well received in West Michigan. It allows Pine Rest and Mercy Health to serve the community's acute psychiatric needs, including commercial, Medicare and Medicaid populations, and to strengthen Pine Rest's and Mercy Health's ability to further their mission to provide high quality psychiatric care in a healing, Christian environment.

Pine Rest is also a member of the Spectrum Health Regional Hospital Network. The network is comprised of 22 West Michigan hospitals who's mission is to "improve the health status of our communities."